California Privacy Statement, Methodology. Characterization of hydration products of mineral trioxide aggregate. Hecova et al. Dent Mater. Reporting clinical or radiographic success rates. With its consistent success rate with MTA and better biocompatibility than MTA, PRF would be a good substitute for MTA and CH in the treatment of pulp exposure in immature permanent teeth. 27 studied 889 permanent teeth of 384 children and adult patients, in which 22 teeth were treated with pulpotomy (13 teeth had immature apices and nine had mature apices). Only one study [17] included traumatized teeth and carious teeth, all of the other four studies only included carious teeth [15, 16, 18, 19]. Only Eppa 2018 compared MTA with triple antibiotic paste and abscess remedy at 1, 3, 6, 9, 12, 18, 24 months [19]. The following search strategy was adapted for each database search: (pulpotomy OR pulpotomies OR pulp therapy OR pulp treatment OR pulp exposure) AND (permanent OR adult OR secondary) AND (random*), limited in ‘English’. Trends Biotechnol. MTA is considered superior to CH in clinical and radiographic aspects in primary molar as a result of better biocompatibility of MTA [24]. Parhizkar A, Nojehdehian H, Asgary S. Triple antibiotic paste: momentous roles and applications in endodontics: a review. Immature permanent teeth Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis | springermedizin.de Pulpotomy is one of the most widely used methods in preserving vital pulp in teeth, which is of great significance in achieving continue root formation in immature permanent teeth suffering from dental caries or trauma. mended to treat immature permanent teeth with necrotic pulp tissue and/or apical periodontitisor an abscess. Conclusions: Partial pulpotomy, performed with MTA or CH used as the pulp-capping material following hemostasis with SH or SS solutions, provided comparable and favorable outcomes in carious pulp exposures of immature permanent teeth. These failed cases were reported at 3 months. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Accessed 5 June 2019. Camilleri J. The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats. While in the CH group, it was a 97.4% success rate at the same two follow up periods (38 out of 39, 1 tooth dropped out at 6 months). Farto J, Canalda CS, Boj JR. Microleakage of MTA in primary molar pulpotomies. Preserving the pulp is important in the treatment of carious pulp exposure in young permanent teeth. To assess the outcome of mineral trioxide aggregate (MTA) complete pulpotomy in permanent teeth with carious exposures. Results were consistent in the 6-month and 12-month follow-ups that no significant difference was observed between the use of MTA and CH. All teeth are immature when they erupt. Hecova et al. All of the included studies were evaluated to have a high risk of bias due to the types of interventions that do not permit the blinding of the operators. The analysis was performed using the Review Manager 5.3 software provided by the Cochrane Collaboration. iron or bismuth) [38] was not reported in the included studies, which might be a result of limited follow-up time or the insufficient number of subjects. The sample sizes varied from 30 to 80 teeth. Both El-Meligy 2006 and Özgür 2017 compared MTA with CH. 2014 Aug 6;(8):CD003220. Performance bias, under this circumstance, seems unavoidable. Also, the studies should have at least 6 months of follow-up, report clinical and radiographic success in detail and publish in English. Five RCTs were included for a systematic review, and all of them had a high risk of bias. However, it also has its drawbacks, including discoloration of teeth [6], high pH during the procedure [7], high cost and high technical sensitivity [8, 9]. Based on the current limited evidence, MTA and CH had similar outcome of pulpotomy in immature permanent teeth, which was consistent with previous research in permanent teeth with closed apices [12] but different with the conclusion drawn by previous systematic review in primary molars [13]. BMC Oral Health 19, 227 (2019). Int Endod J. Pulpotomy in caries-exposed immature permanent molars using calcium-enriched mixture cement or mineral trioxide aggregate: a randomized clinical trial. After screening titles and abstracts, a full-text assessment of 12 articles was conducted by 2 independent investigators (inter-reviewer agreement, kappa = 0.91). (2)Associate professor, … Vital pulp therapies have been used in primary teeth and immature permanent teeth. The most obvious limitation of this review is the small number of included studies and that the small sample size of all the included studies. Four studies had a low risk of detection bias [15,16,17,18], as they reported the blinding of the investigator, whereas the remaining study was assessed as unclear risk of detection bias as they did not mention whether the investigator was blinded [19]. Council on Clinical Affairs (2014) Pulp therapy for primary and immature permanent teeth –guideline of American Academy of pediatric dentistry . Camp JH, Fuks AB. Immature permanent teeth are prone to caries and trauma which can cause exposure and degeneration of pulp. There were no statistical differences between the two groups in terms of clinical and radiographic success at all follow-up periods (P > 0.05). We treated each tooth or root as units of analysis, and clinical and radiographic success rates were derived in this systematic review using the same criteria: deleting drop-outs and only considering patients who recalled. Treatments were considered successful in all cases according to the following criteria: absence of clinical symptoms, … Both MTA and Biodentine are considered as bioactive … Based on these studies, similar success rates with MTA were found between the dressing agents CH, CEM, RPF and TAP as pulpotomy-dressing agents in the treatment of immature permanent teeth. YW contributed to the overall conceptualization and design of the study, served as a reviewer to resolve issues of disagreements in the selection of papers, and revised the manuscript. If the pulpotomy treatment is about to succeed, microbiota should be properly reduced, abscess remedy and TAP both function as antibacterial agents to improve the treatment outcome [26]. To conclude, there are limited publications in this field and bias might affect the accuracy of conclusions drawn from the aforementioned studies. There was no significant clinical heterogeneity between the two studies, so we pooled their data at 6 and 12 months. The references of all included articles or relevant reviews were cross-checked. Currently available procedures include direct pulp capping, complete pulpotomy and partial pulpotomy. 1993;15:257–259. It is more likely to have a high success rate in baby teeth and an immature permanent tooth that is vital to an older permanent tooth. Pulp degeneration stops root … Group I consisted of 31 teeth no … 2013;7:2644–6. Young permanent teeth Partial Pulpotomy for Carious Exposures Partial pulpotomy is also indicated in young permanent teeth with pulp exposure due to caries, provided that the bleeding can be controlled within several minutes. Mçjàre I, Cvek M. Partial pulpotomy in young permanent teeth with deep carious lesions. 2010;36:16–27. There is little difference in success rate between mineral trioxide aggregate (MTA) and calcium hydroxide (CH) at 6-month follow-up (risk ratio (RR) 1; 95% confidence interval (CI) 0.94 to 1.06) and 12-month follow-up (RR 1.04; 95% CI 0.96 to 1.13). This site needs JavaScript to work properly. Abuelniel et al conducted a prospective randomized clinical trial comparing mineral trioxide aggregate (MTA) and Biodentine as pulpotomy medicaments in traumatized immature permanent teeth. We also found that the criteria for radiographic success differed among the included studies, which also hindered the data synthesis. Pulpotomy is one of the most widely used methods in preserving vital pulp in teeth, which is of great significance in achieving continue root formation in immature permanent teeth suffering from dental caries or trauma. Siddiqui SH, Mohamed AN. In partial pulpotomy (Cvek pulpotomy), 2 mm of the pulp below the exposure are removed, leaving a wound of healthy pulp, where dressing should be … Clipboard, Search History, and several other advanced features are temporarily unavailable. More high-quality randomized controlled trials evaluating the effect of different pulpotomy dressing agents on immature permanent teeth with pulp exposure to dental caries or trauma are required. Lin PY, Chen HS, Wang YH, et al. Asgary S, Eghbal M, Parirokh M. Sealing ability of anovel endodontic cement as a root-end fillingmaterial. 2010;36:400–13. 2020 Sep;21(3):108-109. doi: 10.1038/s41432-020-0126-2. (a) (b) (c) (d) Figure 3 Radiographic … More high-quality RCTs are needed in this field in future studies. PubMed Central  2018;1:1–6. doi: 10.1016/j.dental.2011.04.010.  |  http://www.aapd.org/media/Policies_Guidelines/BP_PulpTherapy.pdf, https://www.aae.org/specialty/clinical-resources/guide-clinical-endodontics/, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/, https://doi.org/10.1186/s12903-019-0917-z, Dental techniques; tools, materials and surgical research. Peadiatic dentists may consider cost-effectiveness when choosing pulpotomy-dressing agents in clinics. [18] Asgary S, Eghbal MJ, Ehsani S. Periradicular regeneration after endodontic surgery with calcium-enriched mixture cement in dogs. Calcium-enriched mixture (CEM) [10], platelet-rich fibrin (PRF) [11] and antibiotics mixture such as triple antibiotic paste (TAP) are also administered in the treatment of pulpotomy in immature permanent teeth. 2014 Nov;42(11):1390-5. doi: 10.1016/j.jdent.2014.06.007. The selection of agent can influence the success rate of vital-pulp therapy [3]. 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